Association between Obesity, Race, and Luminal Subtypes of Breast Cancer

Abstract

This study emphasizes on the complex relationship between obesity, race, and different types of breast cancer, focusing on the differences between Luminal A and Luminal B tumors. Drawing on broad research studies that analyzed large quantities of epidemiological data and utilizing different statistics from logistic regression to mediation and comparison of subgroups, the study clarifies the biological pathways of estrogen metabolism, adipokines and chronic inflammation and the societal such as health care access, socioeconomic standing, and cultural views of body weight. Both obesity and race are determined by the outcomes to be predictors of risk and prognosis of the more aggressive Luminal B breast cancers. It is optimal to couple medical treatment with social initiative to reducing inequalities in society. Finally, the results can be employed to enhance risk evaluation, tailored screening initiatives and policies that aim to mitigate the additional burden of breast cancer that rises especially among vulnerable populations.